Most common and frequent last names and surnames in the state of Tlaxcala
The following last names and surnames are the most frequent and common in the Mexican State of Tlaxcala. Please click on each of them to obtain more information.
| Ranking position | Last name | Number of inhabitants with the father's last name | Number of inhabitants with the mother's last name | Total number of inhabitants |
| 1 | Hernández | 50681 | 51753 | 102434 |
| 2 | Pérez | 35560 | 35817 | 71377 |
| 3 | Sánchez | 32204 | 32042 | 64246 |
| 4 | Flores | 24142 | 23793 | 47935 |
| 5 | López | 21894 | 21423 | 43317 |
| 6 | García | 20906 | 21534 | 42440 |
| 7 | Rodríguez | 18089 | 18139 | 36228 |
| 8 | Vázquez | 15381 | 14609 | 29990 |
| 9 | González | 15155 | 16225 | 31380 |
| 10 | Morales | 13442 | 13060 | 26502 |
| 11 | Ramírez | 13133 | 13139 | 26272 |
| 12 | Romero | 11458 | 11620 | 23078 |
| 13 | Martínez | 11004 | 12456 | 23460 |
| 14 | Muñoz | 10920 | 10783 | 21703 |
| 15 | Juarez | 10919 | 10962 | 21881 |
| 16 | Rojas | 7094 | 7384 | 14478 |
| 17 | Díaz | 6814 | 6995 | 13809 |
| 18 | Cruz | 6332 | 7064 | 13396 |